The Speakers
Section 01
Basic science of astrocytes in vitro/preclinical
Luc Pellerin
Lausanne University, Switzerland
Anne-Karine Bouzier-Sore
Centre RMSB, France
Sarah Jolly
University College London, UK
Eduardo R. Zimmer
UFRGS, Brazil
Section 02
Radiochemistry/design, translation, preclinical and human
Salvatore Bongarzone
King’s College London, UK
Diana Cash
King’s College London, UK
Igor Fontana
UFRGS, Brazil/King’s College London, UK
Section 03
In vivo astrocyte biomarkers
Nick Ashton
Gothenburg University, Sweden
Elena Rodriguez Vieitez
Karolinska Institute, Sweden
Christine Parker
GSK/Imperial College London
Paul Edison
Imperial College London, UK
Programme
26th September
3 sessions; ~15min talks with open discussion/questions after each
08:30 – 09:00 | Registration
09:00 – 09:15 | Intro, thank sponsor(s), housekeeping etc
09:15 – 10:45
Section 1 – Basic science of astrocytes in vitro/preclinical
Luc Pellerin | Lausanne University, Switzerland
Astrocytes as activity-dependent lactate suppliers for neurons: Key role for MCT4
Anne-Karine Bouzier-Sore | Centre RMSB, France
Importance of astrocytic lactate in brain metabolism: from functional brain imaging to neuroprotection
Sarah Jolly | University College London, UK
Targeting astrocytes in neurodegenerative diseases: from basic science to drug discovery
Eduardo R. Zimmer | UFRGS, Brazil
Astrocyte glutamate transport drives [¹⁸F]FDG-PET signal
10:45 – 11:15 | Coffee break
11:15 – 12:15
Section 2 – Radiochemistry/design, translation, preclinical and human
Salvatore Bongarzone | King’s College London, UK
What we need to know to design a CNS PET radiotracer
Diana Cash | King’s College London, UK
Preclinical imaging and neuroinflammatory biomarkers
Igor Fontana | UFRGS, Brazil/King’s College London, UK
Development of Carbon-11 PET Pro-Radiotracer for Imaging the Astroglial Excitatory Amino Acid Transporter
12:15 – 13:15 | Lunch - Buffet provided
13:15 – 14:45
Section 3 – In vivo astrocyte biomarkers
Nick Ashton | Gothenburg University, Sweden
The current status of fluid biomarkers in Alzheimer's disease and related disorders.
Elena Rodriguez Vieitez | Karolinska Institute, Sweden
PET imaging of astrocytosis using [¹¹C]-deuterium-L-deprenyl in translational and multimodal studies
Christine Parker | GSK/Imperial College London, UK
Development of a PET Ligand Targeting the Imidazoline-I2 Binding site – a potential astrocytic marker?
Paul Edison | Imperial College London, UK
Evaluation of astroglial activation using novel [11C]-BU99008 PET
14:45 – 15:15 | Tea
15:15 – 16:30 | “Open Mic” &/or group discussions to promote collaboration
16:30 – 17:00 | Wrap-up/final discussion
The Venue
St Thomas' Hospital
4th floor Lambeth wing.
Westminster bridge road, SE17EH
London, UK
Acknowledgment
